Seleucia in Pieria also known in English as Seleucia by the Sea, and later named Suedia, was a Hellenistic town, the seaport of Antioch ad Orontes (Syria Prima), the Seleucid capital, modern Antakya (Turkey). The city was built slightly to the north of the estuary of the river Orontes, between small rivers on the western slopes of the Coryphaeus, one of the southern summits of the Amanus Mountains.
According to Pausanias and Malalas, there was a previous city here named Palaeopolis ("Old City"). At present, it is located at the seaside village of Çevlik near the town of Samandağ in the Hatay Province of Turkey. Seleucia, Apamea, Laodicea, and Antioch formed the Syrian tetrapolis.
Seleucia Pieria was founded in ca. 300 BCE by Seleucus I Nicator, one of the successors of the Macedonian conqueror Alexander the Great and the founder of the Seleucid Empire. The Macedonians called the landscape Pieria, after a district in their homeland that was also between the sea and a mountain range (the Olympus).
When Seleucus I was murdered on his way to Macedon in 281 BC, his son, Antiochus I, buried his ashes in a building called "Nikatoreion", situated on Seleucia.
The city was of great importance in the struggle between the Seleucids and the Ptolemies; it was captured by Ptolemy Euergetes in 246 BCE. As the Ptolemies (Lagids) and Seleucids fought over the city, it changed hands several times until 219 BCE, when the Seleucid Antiochus III the Great recaptured it during the Fourth Syrian War (219–217 BCE); his general Ardys is recorded as having distinguished himself during the siege. Then it obtained its freedom and kept it even to the end of the Roman occupation. It had long enjoyed the right of coinage.
When the Seleucid Empire was subdued by the Armenian conqueror Tigranes II, Seleucia Pieria resisted. Roman general Pompey the Great restored the Seleucids to power by giving the city to Antiochus I Theos of Commagene, a direct descendant of Seleucus I Nicator and a loyal ally of Rome. Under light Commagene rule, Seleucia enjoyed substantial autonomy, i.e. de facto independence.
Seleucia's importance grew significantly over time, necessitating the enlargement of its harbours several times under Diocletian and Constantius. These harbours, called the "inner" and "outer" harbours, served from time to time the Roman navy.
The city was Christianized early. As the port of Antioch of Syria, "Seleucia on sea"—so called to distinguish it from other cities of the same name—is most notable as the precise point of embarkation from which the Apostle Paul [in 45 CE] and Saint Barnabas sailed from this port on their first missionary journeys, as chronicled in the Bible (Acts 13:4). At the end of that same journey he must have made landfall at Seleucia before going to Antioch (see Acts 14:26). His route at the beginning of the second journey was by land and probably bypassed Seleucia (see Acts 15:40–41), though on returning, he must have passed through it again (see Acts 18:22). Once more taking a land route when setting out on his third journey, Paul may have missed Seleucia (see Acts 19:1), and at that journey's end he did not return to Antioch and so missed Seleucia again (see Acts 21:7–8). This means that Paul passed through Seleucia at least three times, and probably several more on pre-missionary visits to Antioch of Syria (see Acts 11:26; 12:25).
The oldest bishop known is Zenobius, present at the Council of Nicaea in 325 CE. Other known bishops include Eusebius, an Arian, and Bizus in the fourth century, with twelve others cited by Le Quien (Oriens Christianus, II, 777–780). In the sixth century CE the Notitia Episcopatuum of Antioch, gives Seleucia Pieria as an autocephalous archbishopric, suffragan of Antioch (Échos d'Orient, X 144); the diocese existed until the tenth century CE, and its boundaries are known (Échos d'Orient, X, 97). For some Roman Catholic titularies see Eubel, Hierarchia catholica medii aevi, I, 468.
Seleucia Pieria was a diocese of the Syriac Orthodox Church in the eighth and ninth centuries CE, three of whose bishops are known. The last-known Syriac Orthodox bishop of Seleucia, Ahron (847/874 CE), is mentioned in the lists of Michael the Syrian. There were also Georgian monastic establishments around Seleucia from the 11th to the 13th centuries.
The city is still a titular see of the Roman Catholic Church, Seleuciensis Pierius; the seat is vacant following the death of the last bishop in 1980.